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How SR-9009 and the process of autophagy burns fat

SR-9009 (Stenabolic) is a research chemical that is being studied for its potential to induce autophagy, which is the process by which the body's cells break down and recycle old and damaged components. The exact mechanism by which SR-9009 induces autophagy is not fully understood, but research suggests that it may work by activating a protein called REV-ERB, which plays a role in regulating the body's circadian rhythm.


Activation of REV-ERB is thought to increase the expression of genes involved in autophagy, including the gene encoding the protein autophagy-related protein 7 (ATG7). Studies in cells and animals have shown that SR-9009 can increase the expression of ATG7, leading to an increase in autophagy.


SR-9009 is also known to regulate the levels of glucose and fatty acids in the liver, which can lead to the activation of autophagy in the liver cells. This can help remove damaged or dysfunctional cellular components, which can promote overall cellular health and function.

It is important to note that SR-9009 is a research chemical and has not been approved for human use.


Inducing autophagy through use of SR-9009 will assist with fat loss. When autophagy is activated, the body's cells are able to remove and recycle damaged fat cells, which can help to reduce overall body fat. Additionally, when autophagy is activated, cells can also reduce the production of new fat cells and improve the metabolism of existing fat cells.


Research in animals has suggested that inducing autophagy through SR-9009 can lead to weight loss and reduced body fat. Studies have also shown that SR-9009 can improve the body's ability to burn fat and improve overall metabolic function, which may further contribute to fat loss.


In conclusion, SR-9009 is a research chemical that is being studied for its potential to induce autophagy. The exact mechanism by which it induces autophagy is not fully understood, but research suggests that it may work by activating a protein called REV-ERB, which plays a role in regulating the body's circadian rhythm and by regulating the levels of glucose and fatty acids in the liver. However, SR-9009 is not approved for human use and more research is needed to fully understand its potential effects and safety.


Sources:

  1. Dodson B (2013-08-20). "New drug mimics the beneficial effects of exercise". Gizmag. Retrieved 2013-08-21.

  2. ^ Solt LA; Wang Y; Banerjee S; Hughes T; Kojetin DJ; Lundasen T; Shin Y; Liu J; Cameron MD; Noel R; Yoo SH; Takahashi JS; Butler AA; Kamenecka TM; Burris TP (May 2012). "Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists". Nature. 485 (7396): 62–8. Bibcode:2012Natur.485...62S. doi:10.1038/nature11030. PMC 3343186. PMID 22460951.

  3. ^ Woldt E; Sebti Y; Solt LA; Duhem C; Lancel S; Eeckhoute J; Hesselink MK; Paquet C; Delhaye S; Shin Y; Kamenecka TM; Schaart G; Lefebvre P; Nevière R; Burris TP; Schrauwen P; Staels B; Duez H (August 2013). "Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy". Nat. Med. 19 (8): 1039–46. doi:10.1038/nm.3213. PMC 3737409. PMID 23852339.

  4. ^ "Prohibited List". 2014-07-22.

  5. ^ Mazzarino M, Rizzato N, Stacchini C, de la Torre X, Botrè F (November 2018). "A further insight into the metabolic profile of the nuclear receptor Rev-erb agonist, SR9009". Drug Test Anal. 10 (11–12): 1670–1681. doi:10.1002/dta.2538. hdl:11573/1291262. PMID 30395700.



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